Star striker Sergio Aguero is in danger of missing a crucial stage of the season after suffering a knee ligament injury.
The prolific Argentinian has scored 19 times this season.
Aguero had managed to get to his feet following a Seamus Coleman tackle early during Manchester City's 1-0 home win over Everton yesterday morning (Singapore time) but, moments later, his knee appeared to jar as he stretched for the ball while under pressure from Muhamed Besic.
The 26-year-old was in tears on the sidelines.
He needs to be assessed before City know the full extent of the damage, but manager Manuel Pellegrini is already expecting him not travel to Italy to play Roma in the Champions League on Thursday morning.
That is a major blow for the English champions, who already have a number of injury and suspension problems for the decisive final group game.
Said Pellegrini: "He has a problem in his ligament, in his knee. We will see tomorrow how serious it is but it's not good news, I don't think he will be able to play next week.
"We must wait for the doctor, but the important thing is he will not be playing against Roma and it's a very important game for us.''
Former England striker Alan Shearer sang Aguero's praises.
He said on the BBC: "Sergio Aguero has been incredible for Manchester City this season.
"He has produced the goods week after week. It would be a massive blow if he is out. I have to admit that I did fear the worst when I saw the physio, but I hope it's not too bad."
- Wire Services.