A patient's chance for a liver transplant is now better
The operation involved a living donor and incompatible blood groups
Patients needing a liver transplant now have a higher chance of receiving a donor organ, following the success of South-east Asia's first liver transplant involving a living donor with an incompatible blood group.
Doctors at Singapore General Hospital (SGH) believe that with the patient recovering well from last year's surgery, it will pave the way for similar surgery to be carried out both in the region and Singapore.
In Singapore, there is a growing number of patients on the waiting list for a liver, from nine in 2007 to 52 as of end June this year, based on statistics from the National Organ Transplant Unit.
Associate Professor Jeyaraj Prema Raj, director of the Liver Transplant Programme at SGH, said that such a transplant is an important option to have, especially for families in dire need - as was the case of Mr Chen Yu Hui, 56.
Without a transplant, doctors predicted that Mr Chen, who was suffering from liver cancer hepatitis B and liver cirrhosis, had less than two years to live.
CHANCE OF RECURRENCE
The elder Mr Chen did not qualify for a liver from a deceased donor as such livers are prioritised for liver cancer patients with the least likely chance of recurrence. In Mr Chen's case, there was concern that his cancer could recur.
Blood group incompatible organ transplants are usually a last resort, said Prof Prema Raj. But it was left to Mr Chen's 32-year-old son Qingzhong to come to his aid. A part of the son's liver was transferred to the father in a 12-hour operation at SGH in July last year.
The elder Mr Chen has B positive blood while his son is A positive.
Preparing the elder Mr Chen for the surgery involved suppressing the production of and removing specific antibodies in his blood - through an intravenous infusion and special dialysis machine - to a level low enough to prevent them from thinking of the donated organ as a foreign body and attacking it.
While kidney transplants involving living donors with blood groups incompatible with that of recipients have been performed in Singapore since 2008, this was the first such liver transplant.
As such, the surgical team studied blood group incompatible liver transplants in other countries such as Korea and Japan.
The younger Mr Chen and his 34-year-old brother volunteered as potential donors but the younger Mr Chen was deemed more suitable.
The owner of a retail shop became a father for the first time when his son was born in November last year.
More than a year later, the duo are both recovering well and continue to go for follow-up medical checks.
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